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FDA approves new version of diabetes drug Mounjaro for weight loss

Published Mon, 25 Nov 2024 05:02:47 GMT

A new version of the popular diabetes treatment Mounjaro can be sold as a weight-loss drug, U.S. regulators announced Wednesday.The U.S. Food and Drug Administration approved Eli Lilly’s Zepbound, or tirzepatide. The drug helped dieters lose about a quarter of their body weight, or 60 pounds (27 kilograms), in a recent study.Zepbound is the latest diabetes drug approved for weight loss, joining Novo Nordisk’s Wegovy, a high-dose version of its diabetes treatment Ozempic. The F DA approved Lilly’s drug for people who are considered obese, with a body mass index of 30 or higher, or those who are overweight with a related health condition, like high blood pressure, high cholesterol or diabetes. The drug should be paired with a healthy diet and regular exercise, the FDA said. In the U.S., at least 100 million adults and about 15 million children are considered obese.The drug tirzepatide in Zepbound and Mounjaro and semaglutide in Wegovy and Ozempic work by mimicking ho...

Toronto man charged after traffic stop leads to Niagara police seizing $20,000 in fentanyl

Published Mon, 25 Nov 2024 05:02:47 GMT

A Toronto man is facing drug-related charges after Niagara police located over 100 grams of fentanyl in his vehicle during a traffic stop.Officers were on patrol in the King Street and Third Street area in Welland, Ont. just before 11 p.m. on Tuesday when they noticed the driver of a 2018 Hyundai Elantra. Niagara police said a traffic stop was conducted, resulting in the driver exiting their vehicle and becoming argumentative with an officer. It’s alleged the driver couldn’t produce proper photo identification and only verbally provided his name when prompted.Investigators said the man’s verbal name did not match the Ministry of Transportation (MTO) database, and he was arrested at the scene. Police searched the suspect’s vehicle, which resulted in the recovery of 103.2 grams of suspected fentanyl. Officers also noted that a photo ID belonging to the driver was recovered, confirming the name previously provided was false.On Wednesday, the man was identified a...

Commercial fishing groups sue 13 US tire makers over rubber preservative that’s deadly to salmon

Published Mon, 25 Nov 2024 05:02:47 GMT

TACOMA, Wash. (AP) — The 13 largest U.S. tire manufacturers are facing a lawsuit from a pair of California commercial fishing organizations that could force the companies to stop using a chemical added to almost every tire because it kills migrating salmon.Also found in footwear, synthetic turf and playground equipment, the rubber preservative 6PPD has been used in tires for 60 years. As tires wear, tiny particles of rubber are left behind on roads and parking lots, breaking down into a byproduct, 6PPD-quinone, that is deadly to salmon, steelhead trout and other aquatic wildlife when rains wash it into rivers.“This is the biggest environmental disaster that the world doesn’t quite know about yet,” said Elizabeth Forsyth, an attorney with the environmental law firm Earthjustice, which is representing the fishing groups. “It’s causing devastating impacts to threatened and endangered species.”The Institute for Fisheries Resources and the Pacific Coast Federation of Fishermen’s As...

Missouri Supreme Court hears case on latest effort to block Planned Parenthood funding

Published Mon, 25 Nov 2024 05:02:47 GMT

JEFFERSON CITY, Mo. (AP) — The Missouri Attorney General’s Office defended the Republican-led Legislature’s latest attempt in a years-long struggle to block taxpayer dollars from going to Planned Parenthood during arguments before the state Supreme Court on Wednesday.Republican Attorney General Andrew Bailey’s office had appealed after a lower court judge found it was unconstitutional for lawmakers in 2022 to specify that Planned Parenthood would get zero dollars for providing family planning services to Medicaid patients despite reimbursing other health care providers for similar treatments.Solicitor General Josh Divine told Supreme Court judges that creating a state budget is a core power granted to lawmakers. Divine said if the high court rules in favor of Planned Parenthood in this case, it will “wreck the appropriation process that has been used for decades.”Chuck Hatfield, Planned Parenthood’s lawyer, told judges that’s “not so.” He said the case ...

No, Dior didn’t replace Bella Hadid with an Israeli model over her comments on the Israel-Hamas war

Published Mon, 25 Nov 2024 05:02:47 GMT

Social media users are sharing a baseless claim that Dior has dropped Bella Hadid due to the supermodel’s recent comments on the latest Israel-Hamas war. Here are the facts:CLAIM: Dior has ended its partnership with Bella Hadid because she posted a message of support for Palestinians, and the brand replaced her in a new ad campaign with Israeli model May Tager.AP’S ASSESSMENT: False. Hadid’s contract with the luxury fashion house ended in March 2022, long before the latest conflict, a person close to the matter told The Associated Press. And while Tager is one of several models appearing in Dior’s 2023 holiday campaign, she was also in the 2022 version — and both ads more prominently featured actor Anya Taylor-Joy.THE FACTS: Hadid, whose father is Palestinian, has repeatedly made public remarks criticizing the Israeli government and supporting Palestinians in the years since she was named a brand ambassador for Dior’s makeup in 2016.After the latest conflict between Israel and Hamas...

3 charged with running sex ring that catered to elected officials, other wealthy clients

Published Mon, 25 Nov 2024 05:02:47 GMT

BOSTON (AP) — Three people have been arrested on allegations that they ran a sophisticated commercial sex ring in Massachusetts and Virginia that catered to well-connected clients such as elected officials and military officers, federal prosecutors said on Wednesday. Prosecutors allege the individuals used two websites and a network of brothels in Massachusetts and eastern Virginia to make hundreds of thousands of dollars. Clients often paid a monthly fee to be part of the “illicit club,” Acting Massachusetts U.S. Attorney Josh Levy told reporters. “This commercial sex ring was built on secrecy and exclusivity, catering to a wealthy and well-connected clientele, and business was booming, until today,” Levy said. Authorities believe potentially hundreds of people bought sex services through the ring, including doctors, lawyers, accountants, elected officials, military officers, government contractors, professors and executives at tech companies, Levy said. “They are the men who...

‘Iconic’ Christmas tree making anticipated return to Toronto’s Eaton Centre

Published Mon, 25 Nov 2024 05:02:47 GMT

After a one-year hiatus, Toronto’s Eaton Centre will once again feature its iconic Christmas tree in the heart of the populous mall. A tree-lighting event will be held next week on Wednesday, Nov. 15, at 6 p.m. Dubbed the tallest tree in North America, the unveiling will be the unofficial kickoff to Toronto’s 2023 holiday season and showcase “[Cadillac Fairview] Winterville.” A ceremony will be hosted by The Barenaked Ladies, who will lead a sing-along performance featuring the Toronto Children’s Chorus onstage. In 2022, Toronto’s Eaton Centre did not showcase the massive Christmas tree due to a roof construction project. “The tree is a special part of the CF Toronto Eaton Centre holiday experience, and after a year-long hiatus, we are thrilled to bring it back — bigger and better than ever,” said Sheila Jennings, General Manager, CF Toronto Eaton Centre. “We have some special plans in the works that we can’t wai...

Defence policy update: Industry demand for clarity has Blair back at drawing board

Published Mon, 25 Nov 2024 05:02:47 GMT

OTTAWA, Kan. — Defence Minister Bill Blair says he recently instructed his team to rejig the Liberals’ long-promised defence policy update, so as to give industry more clarity on long-term spending plans“As the world becomes an increasingly difficult and challenging place, we have to make those investments,” Blair told an industry conference on Wednesday.Blair told a summit held by the Aerospace Industries Association of Canada that the group helped him realize the current plans would not adequately answer questions raised by defence companies.“It’s in part as a result of the meeting I had with you and your team the other day — a couple weeks ago — that I went back to my own team, and I said, ‘We really got to — as we now recraft and refine the defence policy update, it has to be an industry policy as well,'” he said.Blair said that he met with the Prime Minister’s Office “earlier this week” about the new changes to a polic...

Indianapolis Democratic Mayor Joe Hogsett easily wins reelection after expensive race

Published Mon, 25 Nov 2024 05:02:47 GMT

INDIANAPOLIS (AP) — Indianapolis Democratic Mayor Joe Hogsett easily won a third term after an expensive race against a Republican challenger who had a significant fundraising advantage.Hogsett received 59.51% of votes while businessman and former city-county councilman Jefferson Shreve received 40.49% of votes in Tuesday’s election. Hogsett also won the 2015 and 2019 elections by wide margins. The expensive race was marked by the candidates’ stances on national issues, such as abortion and former President Donald Trump, on top of local concerns such as pedestrian safety and the economic development of Indianapolis’s downtown following the COVID-19 pandemic. Both candidates pledged to lobby the Legislature for gun control measures in the state’s largest city. Hogsett was the top federal prosecutor for the Southern District of Indiana before becoming mayor of the city about 880,600 people. The Associated Press emailed Hogsett’s campaign Wednesday seeking a comment o...

Nuvei shares jump nearly 20% after reporting Q3 revenue up more than 50%

Published Mon, 25 Nov 2024 05:02:47 GMT

MONTREAL — Shares in Nuvei Corp. were up nearly 20 per cent in trading Wednesday morning after the company reported its revenue rose more than 50 per cent and raised its financial guidance.The Montreal-based payment technology company, which keeps its books in U.S. dollars, reported late Tuesday it lost US$18.1 million or 14 cents per share for the quarter ended Sept. 30 compared with net income of US$13.0 million or eight cents per share a year earlier.Revenue for the quarter totalled US$304.9 million, up from US$197.1 million in the same quarter last year.On an adjusted basis, Nuvei says it earned 39 cents per diluted share, down from an adjusted profit of 43 cents per diluted share a year earlier.In its outlook, Nuvei says it expects revenue for 2023 between US$1.18 billion and US$1.2 billion, up from earlier expectations for between US$1.17 billion and US$1.2 billion. Adjusted earnings before interest, taxes, depreciation and amortization for the full year are expected between U...